No. As long as you plot at least k=32, those plots will be eligible to win on mainnet. In a decade or more, k=32 may become too small, but that's speculative. Usually the only reason to plot larger than k=32 is to optimize using all of the space on a given drive. For example, it may make sense to have two k=33's and the rest k=32 so that you only leave 10 GB free on a given drive.
